Farnsworth: Step off, you greasers! I was street-racing back when ships still ran on moonwater!
Gang: Damn, yo, get a load of speed geezer!
Farnsworth: Hey! That's it, you hoodlums! Your mouth just wrote a PayPal transfer request that your butt has insufficient funds to honor!
Gang: Yo, it is on! Before that, it was off.
That last line is awesome, totally hilarious. Then there's:
Fry (Sobbing): Poor Bender left me one last voicemail before the Robot Mafia buried him in the desert.
Bender (On cell phone): Fry, old friend, before I die, I just wanted to say... [Beep.] Hang on, I'm getting another call. Hello? [The gun fire commences and Bender screams.]
Hermes: Line up, people! Everyone take a shovel and one sixth of the planet. We'll meet back here in 50 years, our bodies broken and our lives wasted.
Zoidberg: And you say these are free shovels?
Classic zoidberg.
Leela: What? You're gonna wipe out 10% of the galaxy for a stupid golf course?
Mr. Wong: First of all, it 12% . Second, yes, you betcha.
Leela: But you have no idea what life forms might be evolving out there.
Mr. Wong: That's exactly why I'm hiring an impartial scientist to perform an environmental survey. That's him in the money shower.
[Farnsworth is in the money shower, giggling as money rains down around him.]
Into the Wild Green Yonder is a hilarious movie. Probably competes with Roswell That Ends Well as my favorite episode.
From Roswell that Ends Well:
Fry: My God! This means the flying saucer that crashed in Roswell ... was us!
Farnsworth: And the alien they captured was ... was...
[Cut to: Airbase Hangar. Men open a crate. Zoidberg is inside behind some bars. He waves.]
Zoidberg: Hello! [The general winces.] So what are you guys doing tonight? I'm up for whatever.
That episode is excellent. Fry basically goes back in time, kills his grandfather, has sex with his grandmother, and therefore becomes his biological grandfather. Such great stuff.
Though the quality of the show began to wane after the season with the four movies (whichever one that was), Futurama is probably the greatest TV sitcom of all time, and I was sad when it got cancelled.